Expert Informed Introduction to the elements of Psychedelic Assisted Therapy

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An Expert-Informed Introduction to the Elements of Psychedelic-Assisted Therapy

© 2022 BrainFutures – First Edition, August 2022

Introduction:

"It is expected that in the next few years, psychedelic-assisted therapy will become a legal treatment for a variety of behavioral conditions in the United States (Busby, 2022). In anticipation of legal access in clinical settings, in early 2022 BrainFutures released Psychedelic Medicine, a comprehensive review of the clinical literature on psychedelics, which demonstrated notable levels of efficacy in the treatment of conditions as diverse as tobacco addiction and major depression. Following, in Expediting Psychedelic-Assisted Therapy Adoption in Clinical Settings, BrainFutures outlined several major obstacles to bringing this treatment into the United States’ medical system, as well as potential solutions. In this final paper in the series, BrainFutures focuses on the psychotherapeutic aspect of psychedelic-assisted therapy.1 An Expert-Informed Introduction to the Elements of Psychedelic-Assisted Therapy provides an overview of the psychedelic-assisted therapy model that is usually employed in clinical research trials of psychedelic medications. BrainFutures presents the emerging consensus around best practices for psychedelic-assisted therapy in a clinical context as of fall 2022. These conclusions are informed primarily by interviews and input from 22 experts, including academic researchers, clinical trial investigators, and practitioners. We begin by providing a brief overview of treatment designs that have shown efficacy in academic research including studies associated with FDA-approved clinical trials. In the following chapters, we explore the core elements of psychedelic-assisted therapy: screening and assessment, preparation, set and setting, the medication session, and integration. The paper concludes by addressing safety considerations. Each chapter includes a section entitled “The Future of the Field,” which raises questions about how the current model of psychedelic-assisted therapy might be adapted to increase access and/or improve patient outcomes."

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